Cerebral Microvascular Obstruction by Fibrin is Associated with Upregulation of PAI-1 Acutely after Onset of Focal Embolic Ischemia in Rats

The mechanisms underlying cerebral microvascular perfusion deficit resulting from occlusion of the middle cerebral artery (MCA) require elucidation. We, therefore, tested the hypothesis that intravascular fibrin deposition in situ directly obstructs cerebral microcirculation and that local changes i...

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Foilsithe in:J Neurosci
Main Authors: Zhang, Zheng Gang, Chopp, Michael, Goussev, Anton, Lu, Dunyue, Morris, Daniel, Tsang, Wayne, Powers, Cecylia, Ho, Khang-Loon
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 1999
Ábhair:
ARTICLE
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784928/
https://ncbi.nlm.nih.gov/pubmed/10594071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-24-10898.1999
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