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Survival Bias in Mendelian Randomization Studies: A Threat to Causal Inference

It has been argued that survival bias may distort results in Mendelian randomization studies in older populations. Through simulations of a simple causal structure we investigate the degree to which instrumental variable (IV)-estimators may become biased in the context of exposures that affect survi...

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Detalhes bibliográficos
Publicado no:Epidemiology
Main Authors: Smit, Roelof A. J., Trompet, Stella, Dekkers, Olaf M., Jukema, J. Wouter, le Cessie, Saskia
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784762/
https://ncbi.nlm.nih.gov/pubmed/31373921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0000000000001072
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