Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

Granulocyte-macrophage colony-stimulating factor (GM-CSF) has recently emerged as an important pathogenic cytokine in acute graft-versus-host disease (GVHD), but the nature of the T-cell lineages secreting the cytokine and the mechanisms of action are less clear. Here we used interleukin 17A-fate re...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Gartlan, Kate H., Koyama, Motoko, Lineburg, Katie E., Chang, Karshing, Ensbey, Kathleen S., Kuns, Rachel D., Henden, Andrea S., Samson, Luke D., Clouston, Andrew D., Lopez, Angel F., MacDonald, Kelli P. A., Hill, Geoffrey R.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784518/
https://ncbi.nlm.nih.gov/pubmed/31585949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000053
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