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Identifying significantly impacted pathways: a comprehensive review and assessment

BACKGROUND: Many high-throughput experiments compare two phenotypes such as disease vs. healthy, with the goal of understanding the underlying biological phenomena characterizing the given phenotype. Because of the importance of this type of analysis, more than 70 pathway analysis methods have been...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Nguyen, Tuan-Minh, Shafi, Adib, Nguyen, Tin, Draghici, Sorin
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784345/
https://ncbi.nlm.nih.gov/pubmed/31597578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1790-4
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