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A survey of the approaches for identifying differential methylation using bisulfite sequencing data

DNA methylation is an important epigenetic mechanism that plays a crucial role in cellular regulatory systems. Recent advancements in sequencing technologies now enable us to generate high-throughput methylation data and to measure methylation up to single-base resolution. This wealth of data does n...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Brief Bioinform
Main Authors: Shafi, Adib, Mitrea, Cristina, Nguyen, Tin, Draghici, Sorin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171488/
https://ncbi.nlm.nih.gov/pubmed/28334228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx013
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