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Phase II study of trastuzumab with modified docetaxel, cisplatin, and 5 fluorouracil in metastatic HER2-positive gastric cancer

BACKGROUND: Trastuzumab with cisplatin and fluoropyrimidine is the standard treatment in metastatic HER2-positive gastric or gastroesophageal (GE) junction adenocarcinoma, however there is limited data on the efficacy of trastuzumab in combination with a three-drug regimen in this setting. We examin...

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Vydáno v:Gastric Cancer
Hlavní autoři: Mondaca, Sebastian, Margolis, Matthew, Sanchez-Vega, Francisco, Jonsson, Philip, Riches, Jamie C., Ku, Geoffrey Y., Hechtman, Jaclyn F., Tuvy, Yaelle, Berger, Michael F., Shah, Manish A., Kelsen, David P., Ilson, David H., Yu, Kenneth, Goldberg, Zoe, Epstein, Andrew S., Desai, Avni, Chung, Vincent, Chou, Joanne F., Capanu, Marinela, Solit, David B., Schultz, Nikolaus, Janjigian, Yelena Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784321/
https://ncbi.nlm.nih.gov/pubmed/30088161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10120-018-0861-7
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