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Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem cell–specific chemokine recruitment of T cells and microglia

BACKGROUND: One of the clinical hallmarks of low-grade gliomas (LGGs) arising in children with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is significant clinical variability with respect to tumor growth, associated neurologic deficits, and response to therapy. Numerous factors...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Guo, Xiaofan, Pan, Yuan, Gutmann, David H
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784288/
https://ncbi.nlm.nih.gov/pubmed/31111915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz080
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