The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation

Low-grade gliomas are one of the most common brain tumors in children, where they frequently form within the optic pathway (optic pathway gliomas; OPGs). Since many OPGs occur in the context of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome, we have previously employed Nf1 genetic...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Solga, Anne C, Toonen, Joseph A, Pan, Yuan, Cimino, Patrick J, Ma, Yu, Castillon, Guillaume A, Gianino, Scott M, Ellisman, Mark H, Lee, Da Yong, Gutmann, David H
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564557/
https://ncbi.nlm.nih.gov/pubmed/28525381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17589
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