Defining EGFR amplification status for clinical trial inclusion

BACKGROUND: Precision medicine trials targeting the epidermal growth factor receptor (EGFR) in glioblastoma patients require selection for EGFR-amplified tumors. However, there is currently no gold standard in determining the amplification status of EGFR or variant III (EGFRvIII) expression. Here, w...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: French, Pim J, Eoli, Marica, Sepulveda, Juan Manuel, de Heer, Iris, Kros, Johan M, Walenkamp, Annemiek, Frenel, Jean-Sebastien, Franceschi, Enrico, Clement, Paul M, Weller, Michael, Ansell, Peter, Looman, Jim, Bain, Earle, Morfouace, Marie, Gorlia, Thierry, van den Bent, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784284/
https://ncbi.nlm.nih.gov/pubmed/31125418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz096
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