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Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution

Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Viruses
Hauptverfasser: Petrenko, Valery A., Gillespie, James W., Xu, Hai, O’Dell, Tiffany, De Plano, Laura M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784196/
https://ncbi.nlm.nih.gov/pubmed/31454976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11090785
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