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Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution

Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using tr...

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Publicado no:Viruses
Main Authors: Petrenko, Valery A., Gillespie, James W., Xu, Hai, O’Dell, Tiffany, De Plano, Laura M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784196/
https://ncbi.nlm.nih.gov/pubmed/31454976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11090785
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