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Naja atra Cardiotoxin 3 Elicits Autophagy and Apoptosis in U937 Human Leukemia Cells through the Ca(2+)/PP2A/AMPK Axis

Cardiotoxins (CTXs) are suggested to exert their cytotoxicity through cell membrane damage. Other studies show that penetration of CTXs into cells elicits mitochondrial fragmentation or lysosome disruption, leading to cell death. Considering the role of AMPK-activated protein kinase (AMPK) in mitoch...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Toxins (Basel)
Asıl Yazarlar: Chiou, Jing-Ting, Shi, Yi-Jun, Wang, Liang-Jun, Huang, Chia-Hui, Lee, Yuan-Chin, Chang, Long-Sen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784133/
https://ncbi.nlm.nih.gov/pubmed/31547294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11090527
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