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Naja atra Cardiotoxin 3 Elicits Autophagy and Apoptosis in U937 Human Leukemia Cells through the Ca(2+)/PP2A/AMPK Axis

Cardiotoxins (CTXs) are suggested to exert their cytotoxicity through cell membrane damage. Other studies show that penetration of CTXs into cells elicits mitochondrial fragmentation or lysosome disruption, leading to cell death. Considering the role of AMPK-activated protein kinase (AMPK) in mitoch...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Chiou, Jing-Ting, Shi, Yi-Jun, Wang, Liang-Jun, Huang, Chia-Hui, Lee, Yuan-Chin, Chang, Long-Sen
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784133/
https://ncbi.nlm.nih.gov/pubmed/31547294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11090527
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