A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells

Therapeutic resistance is a major clinical challenge in oncology. Evidence identifies cancer stem cells (CSCs) as a driver of tumor evolution. Accordingly, the key stemness property unique to CSCs may represent a reservoir of therapeutic target to improve cancer treatment. Here, we carried out a gen...

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Publicat a:EMBO Mol Med
Autors principals: Arfaoui, Abir, Rioualen, Claire, Azzoni, Violette, Pinna, Guillaume, Finetti, Pascal, Wicinski, Julien, Josselin, Emmanuelle, Macario, Manon, Castellano, Rémy, Léonard‐Stumpf, Candi, Bal, Anthony, Gros, Abigaelle, Lossy, Sylvain, Kharrat, Maher, Collette, Yves, Bertucci, Francois, Birnbaum, Daniel, Douik, Hayet, Bidaut, Ghislain, Charafe‐Jauffret, Emmanuelle, Ginestier, Christophe
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783652/
https://ncbi.nlm.nih.gov/pubmed/31476112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809930
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