The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling

Tumor initiation, progression, and therapeutic resistance have been proposed to originate from a subset of tumor cells, cancer stem cells (CSCs). However, the current understanding of the mechanisms involved in their self-renewal and tumor initiation capacity remains limited. Here, we report that ex...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Lopez Almeida, Leonor, Sebbagh, Michael, Bertucci, François, Finetti, Pascal, Wicinski, Julien, Marchetto, Sylvie, Castellano, Rémy, Josselin, Emmanuelle, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Borg, Jean-Paul, Santoni, Marie-Josée
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234904/
https://ncbi.nlm.nih.gov/pubmed/30344009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.09.008
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