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Simultaneous detection of multiple DNA damage types by multi-colour fluorescent labelling
Herein we present an assay allowing concurrent detection of oxidative DNA damage and photoproducts. We apply DNA repair enzymes specific for each lesion type to incorporate spectrally distinct fluorescent nucleotides, enableing simultaneous quantification of the lesions on individual DNA molecules....
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| Udgivet i: | Chem Commun (Camb) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783632/ https://ncbi.nlm.nih.gov/pubmed/31482872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc05198h |
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