Novel Function of lncRNA ADAMTS9-AS2 in Promoting Temozolomide Resistance in Glioblastoma via Upregulating the FUS/MDM2 Ubiquitination Axis

BACKGROUND: LncRNAs have been shown to play essential roles in cancer therapeutic response. However, the detailed mechanism of lncRNAs in temozolomide (TMZ) resistance in glioblastoma (GBM) remain to be elucidated. METHODS: To elucidate the mechanism maintaining TMZ resistance, we constructed two TM...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Yan, Yuanliang, Xu, Zhijie, Chen, Xi, Wang, Xiang, Zeng, Shuangshuang, Zhao, Zijin, Qian, Long, Li, Zhi, Wei, Jie, Huo, Lei, Li, Xuejun, Gong, Zhicheng, Sun, Lunquan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783494/
https://ncbi.nlm.nih.gov/pubmed/31632968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00217
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