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HyPer2 imaging reveals temporal and heterogeneous hydrogen peroxide changes in denervated and aged skeletal muscle fibers in vivo

To determine the role of denervation and motor unit turnover in the age-related increase in skeletal muscle oxidative stress, the hydrogen peroxide (H(2)O(2)) specific, genetically-encoded, fluorescent cyto-HyPer2 probe was expressed in mouse anterior tibialis (AT) muscle and compared with ex vivo m...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Staunton, C. A., Owen, E. D., Pollock, N., Vasilaki, A., Barrett-Jolley, R., McArdle, A., Jackson, M. J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783413/
https://ncbi.nlm.nih.gov/pubmed/31595023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51035-w
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