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Distinct PLZF(+)CD8αα(+) unconventional T cells enriched in liver use cytotoxic mechanism to limit autoimmunity(1)

Hepatic immune system is uniquely challenged to mount a controlled effector response to pathogens while maintaining tolerance to diet and microbial antigens. We have identified a novel population of innate-like, unconventional CD8αα(+)TCRαβ(+) T cells in naïve mice and in human peripheral blood, cal...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Sheng, Huiming, Marrero, Idania, Maricic, Igor, Fanchiang, Shaohsuan S., Zhang, Sai, Sant'Angelo, Derek B., Kumar, Vipin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783388/
https://ncbi.nlm.nih.gov/pubmed/31554695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900832
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