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Mycobacterium tuberculosis-induced BAL gene expression signature in latent tuberculosis infection is dominated by pleiotropic effects of CD4+ T cell-dependent IFNγ production despite the presence of polyfunctional T cells within the airways

Tuberculosis (TB) remains a world-wide public health threat. Development of a more effective vaccination strategy to prevent pulmonary TB, the most common and contagious form of the disease, is a research priority for international TB control. A key to reaching this goal is improved understanding of...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jarvela, Jessica, Moyer, Michelle, Leahy, Patrick, Bonfield, Tracey, Fletcher, David, Mkono, Wambura N., Aung, Htin, Canaday, David H., Dazard, Jean-Eudes, Silver, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783366/
https://ncbi.nlm.nih.gov/pubmed/31541022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900230
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