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CD4+ T cell polyfunctional profile in HIV-TB coinfection are similar between individuals with latent and active TB infection

CD4+ T cell counts of HIV-infected individuals with pulmonary TB (PTB) are higher than with other opportunistic infections suggesting that progression to PTB is not merely due to T cell depletion but also dysfunction. There are limited data examining T cell functional signatures in human HIV-TB co-i...

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Detalhes bibliográficos
Publicado no:Tuberculosis (Edinb)
Main Authors: Canaday, David H., Sridaran, Sankar, Van Epps, Puja, Aung, Htin, Burant, Christopher J., Nsereko, Mary, Mayanja-Kizza, Harriet, Betts, Michael R., Toossi, Zahra
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475423/
https://ncbi.nlm.nih.gov/pubmed/25956974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2014.12.008
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