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The gypsy endogenous retrovirus drives non-cell autonomous propagation in a Drosophila TDP-43 model of neurodegeneration

A hallmark of neurodegenerative disease is focal onset of pathological protein aggregation, followed by progressive spread of pathology to connected brain regions. In amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), pathology is often associated with aggregation of TAR DNA Bind...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Chang, Yung-Heng, Dubnau, Josh
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783360/
https://ncbi.nlm.nih.gov/pubmed/31495585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.07.071
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