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The gypsy endogenous retrovirus drives non-cell autonomous propagation in a Drosophila TDP-43 model of neurodegeneration

A hallmark of neurodegenerative disease is focal onset of pathological protein aggregation, followed by progressive spread of pathology to connected brain regions. In amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), pathology is often associated with aggregation of TAR DNA Bind...

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Publicat a:Curr Biol
Autors principals: Chang, Yung-Heng, Dubnau, Josh
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783360/
https://ncbi.nlm.nih.gov/pubmed/31495585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.07.071
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