Cholangiocyte-derived exosomal LncRNA H19 promotes hepatic stellate cell activation and cholestatic liver fibrosis

Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte-derived exosomal-long non-coding RNA-H19 (LncRNA-H19) plays a critical role in promoting cholestatic liver inju...

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Veröffentlicht in:Hepatology
Hauptverfasser: Liu, Runping, Li, Xiaojiaoyang, Zhu, Weiwei, Wang, Yanyan, Zhao, Derrick, Wang, Xuan, Gurley, Emily C., Liang, Guang, Chen, Weidong, Lai, Guanhua, Pandak, William M, Lippman, H. Robert, Bajaj, Jasmohan S., Hylemon, Phillip B., Zhou, Huiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783323/
https://ncbi.nlm.nih.gov/pubmed/30985008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30662
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