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Targeted Mutagenesis of the POU-Domain GeneBrn4/Pou3f4 Causes Developmental Defects in the Inner Ear
Targeted mutagenesis in mice demonstrates that the POU-domain gene Brn4/Pou3f4 plays a crucial role in the patterning of the mesenchymal compartment of the inner ear.Brn4 is expressed extensively throughout the condensing mesenchyme of the developing inner ear. Mutant animals displayed behavioral an...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783103/ https://ncbi.nlm.nih.gov/pubmed/10407036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-14-05980.1999 |
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