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Potentiation of Quantal Catecholamine Secretion by Glibenclamide: Evidence for a Novel Role of Sulphonylurea Receptors in Regulating the Ca(2+) Sensitivity of Exocytosis

Electrochemical detection of quantal catecholamine release from PC-12 cells revealed that glibenclamide, an inhibitor of ATP-sensitive K(+) channels, potentiated Ca(2+)-dependent exocytosis evoked by raised extracellular [K(+)] and by exposure of cells to caffeine. Glibenclamide was without effect o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Taylor, S. C., Carpenter, E., Roberts, M. L., Peers, C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783092/
https://ncbi.nlm.nih.gov/pubmed/10407015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-14-05741.1999
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