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Metabotropic Glutamate Receptor-Mediated Hippocampal Phosphoinositide Turnover Is Blunted in Spatial Learning-Impaired Aged Rats

Maximal phosphoinositide (PI) turnover was examined in the hippocampus of young and aged Long–Evans rats that were behaviorally characterized for spatial learning in the Morris water maze. The type 1 metabotropic glutamate receptor (mGluR) agonist 1S,3R ACPD was used to stimulate PI turnover and to...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nicolle, Michelle M., Colombo, Paul J., Gallagher, Michela, McKinney, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782926/
https://ncbi.nlm.nih.gov/pubmed/10531462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-21-09604.1999
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