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Circuit-Specific Alterations in Hippocampal Synaptophysin Immunoreactivity Predict Spatial Learning Impairment in Aged Rats

The present study examined the long-standing concept that changes in hippocampal circuitry contribute to age-related learning impairment. Individual differences in spatial learning were documented in young and aged Long–Evans rats by using a hippocampal-dependent version of the Morris water maze. Po...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Smith, Thressa D., Adams, Michelle M., Gallagher, Michela, Morrison, John H., Rapp, Peter R.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772954/
https://ncbi.nlm.nih.gov/pubmed/10964964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-17-06587.2000
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