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Age-related spatial learning impairment is unrelated to spinophilin immunoreactive spine number and protein levels in rat hippocampus

Age-related impairments in hippocampus-dependent learning and memory tasks are not associated with a loss of hippocampal neurons, but may be related to alterations in synaptic integrity. Here we used stereological techniques to estimate spine number in hippocampal subfields using immunostaining for...

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Detalles Bibliográficos
Main Authors: Calhoun, Michael E., Fletcher, Bonnie R., Yi, Stella, Zentko, Diana C., Gallagher, Michela, Rapp, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614704/
https://ncbi.nlm.nih.gov/pubmed/17353069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.02.013
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