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Cellular Defects and Altered Gene Expression in PC12 Cells Stably Expressing Mutant Huntingtin

Expanded polyglutamine tracts cause huntingtin and other proteins to accumulate and aggregate in neuronal nuclei. Whether the intranuclear aggregation or localization of a polyglutamine protein initiates cellular pathology remains controversial. We established stably transfected pheochromocytoma PC1...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Li, Shi-Hua, Cheng, Anna L., Li, He, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782329/
https://ncbi.nlm.nih.gov/pubmed/10377328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-13-05159.1999
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