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Lambert-Eaton Antibodies Inhibit Ca(2+) Currents But Paradoxically Increase Exocytosis during Stimulus Trains in Bovine Adrenal Chromaffin Cells

Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease that affects neurotransmitter release at peripheral synapses. LEMS antibodies inhibit Ca(2+) currents in excitable cells, but it is not known whether there are additional effects on stimulus-secretion coupling. The effect of LEMS anti...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Engisch, Kathrin L., Rich, Mark M., Cook, Noah, Nowycky, Martha C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1999
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782246/
https://ncbi.nlm.nih.gov/pubmed/10212298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-09-03384.1999
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