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The Caenorhabditis elegans Gene unc-25Encodes Glutamic Acid Decarboxylase and Is Required for Synaptic Transmission But Not Synaptic Development
The neurotransmitter GABA has been proposed to play a role during nervous system development. We show that theCaenorhabditis elegans gene unc-25encodes glutamic acid decarboxylase (GAD), the GABA biosynthetic enzyme. unc-25 is expressed specifically in GABAergic neurons. Null mutations in unc-25 eli...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782196/ https://ncbi.nlm.nih.gov/pubmed/9880574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-02-00539.1999 |
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