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The Caenorhabditis elegans Gene unc-25Encodes Glutamic Acid Decarboxylase and Is Required for Synaptic Transmission But Not Synaptic Development

The neurotransmitter GABA has been proposed to play a role during nervous system development. We show that theCaenorhabditis elegans gene unc-25encodes glutamic acid decarboxylase (GAD), the GABA biosynthetic enzyme. unc-25 is expressed specifically in GABAergic neurons. Null mutations in unc-25 eli...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Jin, Yishi, Jorgensen, Erik, Hartwieg, Erika, Horvitz, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782196/
https://ncbi.nlm.nih.gov/pubmed/9880574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-02-00539.1999
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