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Molecular Dynamics of the Sodium Channel Pore Vary with Gating: Interactions between P-Segment Motions and Inactivation

Disulfide trapping studies have revealed that the pore-lining (P) segments of voltage-dependent sodium channels undergo sizable motions on a subsecond time scale. Such motions of the pore may be necessary for selective ion translocation. Although traditionally viewed as separable properties, gating...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Bénitah, Jean-Pierre, Chen, Zhenhui, Balser, Jeffrey R., Tomaselli, Gordon F., Marbán, Eduardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782169/
https://ncbi.nlm.nih.gov/pubmed/10024345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-05-01577.1999
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