Metrifonate Increases Neuronal Excitability in CA1 Pyramidal Neurons from Both Young and Aging Rabbit Hippocampus

The effects of metrifonate, a second generation cholinesterase inhibitor, were examined on CA1 pyramidal neurons from hippocampal slices of young and aging rabbits using current-clamp, intracellular recording techniques. Bath perfusion of metrifonate (10–200 μm) dose-dependently decreased both postb...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Oh, M. Matthew, Power, John M., Thompson, Lucien T., Moriearty, Pamela L., Disterhoft, John F.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1999
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782163/
https://ncbi.nlm.nih.gov/pubmed/10024365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-05-01814.1999
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