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Ca(2+)-Induced Deprotonation of Peptide Hormones Inside Secretory Vesicles in Preparation for Release

The acidic environment inside secretory vesicles ensures that neuropeptides and peptide hormones are packaged in a concentrated condensed form. Although this is optimal for storage, decondensation limits release. Thus, it would be advantageous to alter the physical state of peptides in preparation f...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Han, Weiping, Li, Danqing, Stout, Amy K., Takimoto, Koichi, Levitan, Edwin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782154/
https://ncbi.nlm.nih.gov/pubmed/9920653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-03-00900.1999
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