Up regulation of Rho-associated coiled-coil containing kinase1 (ROCK1) is associated with genetic instability and poor prognosis in prostate cancer

Background and objectives: Overexpression of the cytoskeleton-modulating kinase ROCK1 has been associated with unfavorable outcome in many cancers, but its impact in prostate cancer is largely unknown. Results: A weak ROCK1 staining was found in >90% of normal, and cancerous prostate tissues, but...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Steurer, Stefan, Hager, Benjamin, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Minner, Sarah, Clauditz, Till S., Hube-Magg, Claudia, Luebke, Andreas M., Simon, Ronald, Izbicki, Jakob R., Burandt, Eike, Sauter, Guido, Fraune, Christoph, Weidemann, Sören, Schlomm, Thorsten, Heinzer, Hans, Haese, Alexander, Graefen, Markus, Huland, Hartwig, Heumann, Asmus
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781985/
https://ncbi.nlm.nih.gov/pubmed/31557128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102294
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