RNA–DNA Hybrids Support Recombination-Based Telomere Maintenance in Fission Yeast

A subset of cancers rely on telomerase-independent mechanisms to maintain their chromosome ends. The predominant “alternative lengthening of telomeres” pathway appears dependent on homology-directed repair (HDR) to maintain telomeric DNA. However, the molecular changes needed for cells to productive...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genetics
Main Authors: Hu, Yan, Bennett, Henrietta W., Liu, Na, Moravec, Martin, Williams, Jessica F., Azzalin, Claus M., King, Megan C.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2019
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781888/
https://ncbi.nlm.nih.gov/pubmed/31405990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302606
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