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Downregulation of ABCA1 and ABCG1 transporters by simvastatin in cholangiocarcinoma cells

Disturbances in cholesterol homeostasis of the bile duct epithelium, including transport interruption and the hyperaccumulation of intracellular cholesterol can lead to the initiation and progression of cholangiocarcinoma (CCA). Statins, which are lipid-lowering drugs, have been previously documente...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Seeree, Pattaya, Janvilisri, Tavan, Kangsamaksin, Thaned, Tohtong, Rutaiwan, Kumkate, Supeecha
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781495/
https://ncbi.nlm.nih.gov/pubmed/31612028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10874
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