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Downregulation of ABCA1 and ABCG1 transporters by simvastatin in cholangiocarcinoma cells
Disturbances in cholesterol homeostasis of the bile duct epithelium, including transport interruption and the hyperaccumulation of intracellular cholesterol can lead to the initiation and progression of cholangiocarcinoma (CCA). Statins, which are lipid-lowering drugs, have been previously documente...
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| 出版年: | Oncol Lett |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
D.A. Spandidos
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6781495/ https://ncbi.nlm.nih.gov/pubmed/31612028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10874 |
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