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Downregulation of ABCA1 and ABCG1 transporters by simvastatin in cholangiocarcinoma cells

Disturbances in cholesterol homeostasis of the bile duct epithelium, including transport interruption and the hyperaccumulation of intracellular cholesterol can lead to the initiation and progression of cholangiocarcinoma (CCA). Statins, which are lipid-lowering drugs, have been previously documente...

詳細記述

保存先:
書誌詳細
出版年:Oncol Lett
主要な著者: Seeree, Pattaya, Janvilisri, Tavan, Kangsamaksin, Thaned, Tohtong, Rutaiwan, Kumkate, Supeecha
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781495/
https://ncbi.nlm.nih.gov/pubmed/31612028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10874
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