VPS37A directs ESCRT recruitment for phagophore closure

The process of phagophore closure requires the endosomal sorting complex required for transport III (ESCRT-III) subunit CHMP2A and the AAA ATPase VPS4, but their regulatory mechanisms remain unknown. Here, we establish a FACS-based HaloTag-LC3 autophagosome completion assay to screen a genome-wide C...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Takahashi, Yoshinori, Liang, Xinwen, Hattori, Tatsuya, Tang, Zhenyuan, He, Haiyan, Chen, Han, Liu, Xiaoming, Abraham, Thomas, Imamura-Kawasawa, Yuka, Buchkovich, Nicholas J., Young, Megan M., Wang, Hong-Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781443/
https://ncbi.nlm.nih.gov/pubmed/31519728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902170
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