Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine

BACKGROUND: A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolates, 11 years after CQ withdrawal in Southeast Nigeria. METH...

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Udgivet i:Malar J
Main Authors: Ikegbunam, Moses N., Nkonganyi, Charles N., Thomas, Bolaji N., Esimone, Charles O., Velavan, Thirumalaisamy P., Ojurongbe, Olusola
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781387/
https://ncbi.nlm.nih.gov/pubmed/31590670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2977-6
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