Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine

Abstract Background A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolates, 11 years after CQ withdrawal in Southeast Niger...

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Main Authors: Moses N. Ikegbunam, Charles N. Nkonganyi, Bolaji N. Thomas, Charles O. Esimone, Thirumalaisamy P. Velavan, Olusola Ojurongbe
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-10-01
Colecção:Malaria Journal
Assuntos:
Plasmodium falciparum
Drug resistance
Chloroquine
Pfmdr1
Pfcrt
Acesso em linha:http://link.springer.com/article/10.1186/s12936-019-2977-6
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