Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer

Chronic inflammation and gut microbiota dysbiosis, in particular the bloom of genotoxin-producing E. coli strains, are risk factors for the development of colorectal cancer. Here, we sought to determine whether precision editing of gut microbiota metabolism and composition could decrease the risk fo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Zhu, Wenhan, Miyata, Naoteru, Winter, Maria G., Arenales, Alexandre, Hughes, Elizabeth R., Spiga, Luisella, Kim, Jiwoong, Sifuentes-Dominguez, Luis, Starokadomskyy, Petro, Gopal, Purva, Byndloss, Mariana X., Santos, Renato L., Burstein, Ezra, Winter, Sebastian E.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781011/
https://ncbi.nlm.nih.gov/pubmed/31358565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181939
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