Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer

Chronic inflammation and gut microbiota dysbiosis, in particular the bloom of genotoxin-producing E. coli strains, are risk factors for the development of colorectal cancer. Here, we sought to determine whether precision editing of gut microbiota metabolism and composition could decrease the risk fo...

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Publicado en:J Exp Med
Autores principales: Zhu, Wenhan, Miyata, Naoteru, Winter, Maria G., Arenales, Alexandre, Hughes, Elizabeth R., Spiga, Luisella, Kim, Jiwoong, Sifuentes-Dominguez, Luis, Starokadomskyy, Petro, Gopal, Purva, Byndloss, Mariana X., Santos, Renato L., Burstein, Ezra, Winter, Sebastian E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781011/
https://ncbi.nlm.nih.gov/pubmed/31358565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181939
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