Alpha-1-Antitrypsin Ameliorates Pristane Induced Diffuse Alveolar Hemorrhage in Mice

Diffuse alveolar hemorrhage (DAH) is a fatal complication in patients with lupus. DAH can be induced in B6 mice by an intraperitoneal injection of pristane. Since human alpha-1-antitrypsin (hAAT) is an anti-inflammatory and immuno-regulatory protein, we investigated the protective effect of hAAT aga...

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Pubblicato in:J Clin Med
Autori principali: Elshikha, Ahmed S., Abboud, Georges, van der Meijden-Erkelens, Lonneke, Lu, Yuanqing, Chen, Mong-Jen, Yuan, Ye, Ponjee, Godelieva, Zeumer, Leilani, Satoh, Minoru, Morel, Laurence, Song, Sihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780888/
https://ncbi.nlm.nih.gov/pubmed/31470606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8091341
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