Nutritional Therapy Modulates Intestinal Microbiota and Reduces Serum Levels of Total and Free Indoxyl Sulfate and P-Cresyl Sulfate in Chronic Kidney Disease (Medika Study)

In chronic kidney disease (CKD), the gut-microbiota metabolites indoxyl sulfate (IS) and p-cresyl sulfate (PCS) progressively accumulate due to their high albumin-binding capacity, leading to clinical complications. In a prospective crossover controlled trial, 60 patients with CKD grades 3B–4 (GFR =...

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Bibliografiset tiedot
Julkaisussa:J Clin Med
Päätekijät: Di Iorio, Biagio Raffaele, Rocchetti, Maria Teresa, De Angelis, Maria, Cosola, Carmela, Marzocco, Stefania, Di Micco, Lucia, di Bari, Ighli, Accetturo, Matteo, Vacca, Mirco, Gobbetti, Marco, Di Iorio, Mattia, Bellasi, Antonio, Gesualdo, Loreto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780815/
https://ncbi.nlm.nih.gov/pubmed/31510015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8091424
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