Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis

Using next-generation sequencing to decipher methylome and transcriptome and underlying molecular mechanisms contributing to rheumatoid arthritis (RA) for improving future therapies, we performed methyl-seq and RNA-seq on peripheral blood mononuclear cells (PBMCs) from RA subjects and normal donors....

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Bibliographic Details
Published in:J Clin Med
Main Authors: Tseng, Chia-Chun, Lin, Yuan-Zhao, Lin, Chia-Hui, Li, Ruei-Nian, Yen, Chang-Yi, Chan, Hua-Chen, Tsai, Wen-Chan, Ou, Tsan-Teng, Wu, Cheng-Chin, Sung, Wan-Yu, Yen, Jeng-Hsien
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780767/
https://ncbi.nlm.nih.gov/pubmed/31443559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8091284
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