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The Inhibitory Effect of Protamine on Platelets is Attenuated by Heparin without Inducing Thrombocytopenia in Rodents

Protamine sulfate (PS) is a polycationic protein drug obtained from the sperm of fish, and is used to reverse the anticoagulant effect of unfractionated heparin (UFH). However, the interactions between PS, UFH, and platelets are still not clear. We measured the platelet numbers and collagen-induced...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mar Drugs
Päätekijät: Miklosz, Joanna, Kalaska, Bartlomiej, Kaminski, Kamil, Rusak, Malgorzata, Szczubialka, Krzysztof, Nowakowska, Maria, Pawlak, Dariusz, Mogielnicki, Andrzej
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780366/
https://ncbi.nlm.nih.gov/pubmed/31533230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17090539
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