A novel high-throughput molecular counting method with single base-pair resolution enables accurate single-gene NIPT

Next-generation DNA sequencing is currently limited by an inability to accurately count the number of input DNA molecules. Molecular counting is particularly needed when accurate quantification is required for diagnostic purposes, such as in single gene non-invasive prenatal testing (sgNIPT) and liq...

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Vydáno v:Sci Rep
Hlavní autoři: Tsao, David S., Silas, Sukrit, Landry, Brian P., Itzep, Nelda P., Nguyen, Amy B., Greenberg, Samuel, Kanne, Celeste K., Sheehan, Vivien A., Sharma, Rani, Shukla, Rahul, Arora, Prem N., Atay, Oguzhan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779891/
https://ncbi.nlm.nih.gov/pubmed/31591409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50378-8
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